Obesity: Overview of a Universal Health Conundrum
Published: February 1, 2022 | DOI: https://doi.org/10.7860/JCDR/2022/51930.15973
Aparna Pandey, Krishnan Viswanathan, Prabhu Manickam Natrajan, Jayadevan Sreedharan
1. PhD Scholar, Department of Dental, Thumbay Dental Hospital, Ajman, United Arab Emirates.
2. Professor, Department of Periodontology, Rajah Muthiah Dental College and Hospital, Annamalai University, Annamalai Nagar, Tamil Nadu, India.
3. Associate Professor, Department of Periodontology, College of Dentistry, University of Science and Technology of Fujairah, Fujairah, United Arab Emirates.
4. Program Director, Department of Periodontology, Gulf Medical University, Ajman, United Arab Emirates.
Correspondence
Dr. Aparna Pandey,
PhD Scholar, Department of Dental, Thumbay Dental Hospital, Ajman, United Arab Emirates.
E-mail: dr_aparna4@yahoo.co.in
Obesity is a worldwide health issue which is displaying increasing prevalence trend. World Health Organisation (WHO) has already given it as epidemic status. Many physiological parameters such as Body Mass Index (BMI), Waist Circumference (WC), Waist to Hip Ratio (WHR) are used for measurement of obesity. This review was written with the aim to give an inclusive picture of current prevalence of obesity along with discussing the physiology and function of different adipocytes and the numerous chemical messengers released by them. The manifold impact of obesity on various body systems can be elucidated by exploring the adipocytes, adipokines, its functions and signalling mechanism. The adipokines enlist as key players in numerous systemic diseases. Obesity has a significant pathophysiological role in morbidity and mortality causing conditions globally. Obesity can potentially be the leading reason of economic burden on global healthcare, adversely impacting the comprehensive quality of life. This review is an effort to provide a better understanding of the current obesity status and emphasise further researches on its diverse aspects.
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